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The University of Tennessee


L O'Donnell: white matter fiber tracts joined the department of Computer Science and the UT/ORNL Joint Institute for Computational Sciences in 2006, holding positions as tenured faculty in the Department of Electrical Engineering and Computer Science at the University of Tennessee and as senior scientist at Oak Ridge National Laboratory's National Center for Computational Sciences. As a member of the Harvard NeuroDiscovery Center; he served as a visiting faculty in the Department of Radiology's Laboratory for Mathematics in Imaging at Harvard Medical School prior to joining the faculty at UT. His research in computational medicine includes simulation and visualization of biomedical data from the scale of nucleons to atoms to molecules to cells to tissue. Motivating questions include the following.

  • What does the brain look like as it responds to injury?
  • How can simulations of physical processes be visualized?
  • How can petascale data be displayed and comprehended?
  • How can physically based lighting fit in the analysis workflow?

Computational Simulation

Molecular dynamics simulation of constrained water diffusion (I Huff)

3D ensemble space visualization of water in solid state (I Huff)

MD simulation of nanofluid (M Y Hussaini, B Futch)

Simulation of smoke plume rising (K Beason)

Brain Imaging

Tumor (pink) surrounded by white matter fibers (R Kikinis, C Weigle)

Clustered fiber tracts from diffusion MRI (L O'Donnell, C-F Westin)

Dendritic spines from mouse hippocampus (C Ouimet)

CT of skull with highlighted region of interest (K Beason)