Using an Exposome Approach to Assess the Effects of PM2.5 on CVD Outcomes

Co-Principal Investigator:
Michael A. Langston, Department of Electrical Engineering and Computer Science, University of Tennessee
Abstract:
Exposure to fine particulate matter (PM2.5) has been associated with increased morbidity and premature death from cardiovascular disease (CVD) among adults and those already suffering from a wide range of illnesses. Yet little is known about how environmental exposures from across the natural, built and social environments, together with individual behaviors and inherent characteristics, mediate or moderate the effects of PM2.5 and the progression of cardiovascular health and health disparities over the life course. In this project, we use an exposome approach to advance our scientific understanding of the mechanisms and pathways through which environmental exposures and personal characteristics affect the progression of CVD at both individual and population levels over time and space.
Research Partner:
The PI for this project is Paul D. Juarez at Meharry Medical College. A recent team photo is shown below.